Melatonin P.R. tablets from Douglas Laboratories contain 3mg of pure pharmaceutical grade melatonin, in a prolonged-release, bisected tablet.

• Support for healthy sleep cycles*
• Support for normal immune function*
• Natural antioxidant support*

Melatonin is a natural hormone nutrient that is synthesized from the amino acid tryptophan by the pineal gland in the back of the brain. Melatonin also occurs in small amounts in a variety of foods. In the body, melatonin appears to support regulating sleep/wake cycles, supports normal immune function, and supports protecting cells from free radical damage*.

Most of the research on melatonin has focused on its role in providing support for maintaining normal sleep/wake rhythms*. The perception of daylight in the eyes is a signal for the pineal gland to inhibit melatonin synthesis and release.

At night or in the dark, melatonin production rises in the body. The rise in plasma melatonin is thought to be responsible for bringing on sleep. Nocturnal melatonin production is highest in children and begins to decline from adolescence on until it is virtually absent in the elderly.

Melatonin may also support normal immune function by helping maintain the activity of circulating natural killer cells*. Melatonin is considered a potent antioxidant that enters all body cells to help support prevention of free radical damage. In the brain, melatonin is perhaps one of the most important physiological antioxidants. Due to its lipid and water soluble properties, it can freely cross the blood-brain barrier*.