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5 Hydroxytryptophan

Thorne Research
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5 Hydroxy Tryptophan (5 HTP) from Thorne Research may promote serotonin production for improved sleep, mood, and stress management and reduced sugar cravings.

5 Hydroxytryptophan, by Thorne Research

5 Hydroxy Tryptophan (5 HTP) from Thorne Research may promote serotonin production for improved sleep, mood, and stress management and reduced sugar cravings.
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Product Details

Brand: Thorne Research
Category: Vitamins & Supplements
Product Code: 5-hydroxytryptophan-THR
Quantity per Container: Default Title
To further facilitate serotonin production, Thorne Research 5-HTP formula contains pyridoxal 5-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.* 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.
    5-Hydroxytryptophan (5-HTP) is the intermediate metabolite produced when the body initiates the process of converting the essential amino acid L-tryptophan to serotonin. Serotonin levels in the body are associated with the regulation of sleep, mood, aggression, appetite, temperature, sexual behavior, and pain sensation.*
    • Increases serotonin levels for sleep enhancement, decreased sugar cravings, and better stress management*
    • Can be taken with meals without competing with other amino acids
    • Includes vitamin b6 for optimal activity
    • Made without flowing agents that can inhibit bioavailability
    Supplementing with 5-HTP to facilitate serotonin production is preferable to supplementing with L-tryptophan because, unlike L-tryptophan, 5-HTP cannot be shunted into niacin or protein production.*

    Supplementation with 5-HTP bypasses the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase, the rate-limiting step in the synthesis of serotonin and a step that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.

    5-HTP is well absorbed when taken orally, with about 70 percent ending up in the bloodstream.* Intestinal absorption of 5-HTP does not require the presence of a transport molecule and is not affected by the presence of other amino acids; therefore, it may be taken with meals without reducing its usefulness.* 5-HTP easily crosses the blood-brain barrier and usefully increases central nervous system (CNS) synthesis of serotonin.*

    5-HTP has been shown to have a beneficial impact on mood, discomfort associated with fatigue, sleep, and carbohydrate craving.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300mg of 5-HTP daily.*

Suggested Usage

Take 1-2 capsules three times daily or as recommended by a health-care practitioner.

Ingredients

Serving Size: Two Capsules

Two capsules contain:

  • Vitamin B6 (as Pyridoxal 5'-Phosphate) 6.8 mg 400%
  • 5-Hydroxytryptophan 100 mg

Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.

Warnings

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

If pregnant, nursing, or trying to conceive, consult your health-care practitioner before using this product.

5-Hydroxytryptophan should be used with caution in an individual currently taking an SSRI, MAO inhibitor, or other antidepressant medication.

Keep out of reach of children.

Brand: Thorne Research
Category: Vitamins & Supplements
Product Code: 5-hydroxytryptophan-THR
Quantity per Container: Default Title
To further facilitate serotonin production, Thorne Research 5-HTP formula contains pyridoxal 5-phosphate, the active form of vitamin B6 and the necessary cofactor for the conversion of 5-HTP to serotonin.* 5-HTP is commercially produced by extraction from the seeds of the African plant, Griffonia simplicifolia.
    5-Hydroxytryptophan (5-HTP) is the intermediate metabolite produced when the body initiates the process of converting the essential amino acid L-tryptophan to serotonin. Serotonin levels in the body are associated with the regulation of sleep, mood, aggression, appetite, temperature, sexual behavior, and pain sensation.*
    • Increases serotonin levels for sleep enhancement, decreased sugar cravings, and better stress management*
    • Can be taken with meals without competing with other amino acids
    • Includes vitamin b6 for optimal activity
    • Made without flowing agents that can inhibit bioavailability
    Supplementing with 5-HTP to facilitate serotonin production is preferable to supplementing with L-tryptophan because, unlike L-tryptophan, 5-HTP cannot be shunted into niacin or protein production.*

    Supplementation with 5-HTP bypasses the conversion of L-tryptophan into 5-HTP by the enzyme tryptophan hydroxylase, the rate-limiting step in the synthesis of serotonin and a step that can be inhibited by a number of factors, including stress, insulin resistance, increasing age, and deficiencies of vitamin C, folate, and iron.

    5-HTP is well absorbed when taken orally, with about 70 percent ending up in the bloodstream.* Intestinal absorption of 5-HTP does not require the presence of a transport molecule and is not affected by the presence of other amino acids; therefore, it may be taken with meals without reducing its usefulness.* 5-HTP easily crosses the blood-brain barrier and usefully increases central nervous system (CNS) synthesis of serotonin.*

    5-HTP has been shown to have a beneficial impact on mood, discomfort associated with fatigue, sleep, and carbohydrate craving.* Numerous studies of individuals with negative mood status have shown significant positive response with 50-300mg of 5-HTP daily.*

Doctor Trusted Brand
Professional-grade products adhere to the strictest standards for purity and potency, and use the highest-grade ingredients available.
4.3
Rated 4.3 out of 5 stars
Based on 8 reviews
Total 5 star reviews: 5 Total 4 star reviews: 2 Total 3 star reviews: 0 Total 2 star reviews: 0 Total 1 star reviews: 1
88%would recommend this product
8 reviews
  • SH
    Samantha H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    3 years ago
    Works great

    This stuff works great for relaxation. However, be warned if you take it to early u may find yourself waking up in the middle of the night and unable to fall back to sleep.

  • JS
    Judy S.
    Verified Buyer
    I do not recommend this product
    Rated 1 out of 5 stars
    5 years ago
    Waste of my money. It may help some people, just not me

    It did nothing for me. Sorry I bought 2

  • A
    Anonymous
    I recommend this product
    Rated 5 out of 5 stars
    7 years ago
    Thorne 5-Hydroxytryptophan

    AM definitely flattens my mood, keeping me focused all day. PM allows me to nod off at a regular hour. Very cool stuff. Will always take this and recommend.

  • A
    Anonymous
    I recommend this product
    Rated 4 out of 5 stars
    8 years ago
    sleep aide

    It was recommended. By my Acupuncturist. I have have utilizing it for sleep & have been pleased with its effectiveness .

  • A
    Anonymous
    I recommend this product
    Rated 5 out of 5 stars
    10 years ago
    Better Sleep

    Began taking this about 5 months ago. Excellent alternative!